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A one-stop environment for time-conscious executives. Keeping you abreast of the latest developments in the life sciences industry, saving you time and money when you need it most. more

Pharmaceutical Stability Studies as in ICH/CPMP guidelines

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Full manufacturing outsourcing in a complete GMPs/ISO9002 facility

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We can uniquely combine both our experience of staffing and our intricate knowledge of regulatory and clinical device trials. This offers our clients an unprecedented quality of candidates. Our European talent pool is the most comprehensive on the market and contains candidates who may not be accessed via traditional job boards and web advertising. more

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Forced Swim Test (FST) :- The FST is a widely used screening test for antidepressants, the forced swim in rodents, and the tail suspension test in the mouse. It has predictive validity for the detection of substances with potential antidepressant-like activity. In the FST the time spent immobile when rodents placed in a beaker of water from which they cannot escape is measured. Antidepressants decrease the duration of immobility and also increase the latency to immobility, an additional measure that for some classes of antidepressants can increase the sensitivity of this test. more
Social Recognition Task: - Rodents demonstrate a strong preference for social novelty. Social preference tests investigate social tendencies including social memory. Mice habituated in specialised arena with Stranger 1 (S1) in apparatus and a blank apparatus. A novel stranger (S2) is added and the response of the test animal to the novel stranger is analysed (Social Novelty). more
Rotarod: - This task is used to assess motor coordination, and can be used test the effects of drugs on coordination. The apparatus consists of a rotating cylinder that can be set to rotate either at a constant speed or to accelerate. The latency (under constant speed rotation) or the speed (at accelerating rotation) at which the test subject falls from the cylinder is measured. more
The elevated Plus Maze: - is commonly described as a rodent model of anxiety. It is can be used as a screening test for putative anxiolytic or anxiogenic compounds. The test setting consists of a plus sign shaped platform elevated from the floor with two open and two enclosed arms. Aversion to open spaces translates to a restriction of movement to the enclosed arms in the plus maze. Drugs that increase in the proportion of time spent in the open arms and an increase in the proportion of entries into the open arms are potentially anxiolytic. Benzodiazepines such as valium reduce measures of anxiety in the elevated plus maze. more
Morris Water Maze: - The water maze can be used to assess spatial learning and memory. The subjects are placed in a pool of water in a random start location. There is an escape platform hidden under the surface of the water. The subjects will swim in the maze until they have located the platform. During the trials the path length to find the escape platform is recorded. After a number of learning trials the platform is removed, and the percentage of time spent in the quadrant that normally contains the platform is compared to the time spent in other quadrants. more

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