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Out-licensing: Immune related disorders
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Cripto-1 expression increases the expression of TNF-alpha in CD4+ T cells in tissues affected by chronic inflammatory disease. More
This technology is the first to show that subcutaneous administrations of chitosan and an appropriate antigen, with no other component, can be used for enhancing immune responses. More
The present technology describes recombinant poxvirus vectors encoding at least three or more costimulatory molecules and TAAs. More
This TACE inhibitory protein could be used as a new therapeutic agent against chronic inflammatory diseases that are mediated by TNF-alpha. More
Our Australian based clients have developed a second generation antisense inhibitor to human CD49d, a subunit of VLA-4, that has shown in Phase II studies to be effective in reducing brain lesions in patients with the relapsing form of multiple sclerosis. More
These novel pyrazolidinyl compounds can stabilize p53 and induce apoptosis in mammalian cells through selective inhibition of ubiquitin E1. More
These hybrid antibody molecules can be engineered with a variety of small synthetic molecules, and the combination of immunogenic properties results in compounds with powerful target destruction or imaging capabilities. More
New method of cell surface display of single chain antibodies for affinity maturation in a mammalian system More
A method of transfecting isolated autologous T-Lymphocytes with endogenous cytokines, for example IL-7 and IL-15, to sustain an adoptive T-lymphocyte response without systemic toxicity. More
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(website) 48 queries took 66 ms
NrQueryErrorAffectedNum. rowsTook (ms)
1DESCRIBE `licopp`23234
2DESCRIBE `company`27271
3DESCRIBE `condet`17171
4DESCRIBE `countrycode`441
5DESCRIBE `person`15151
6DESCRIBE `account`29291
7DESCRIBE `product_legacy`661
8DESCRIBE `sales_people`661
9DESCRIBE `profile`14141
10DESCRIBE `currencies`775
11DESCRIBE `update_rec`772
12DESCRIBE `user`24241
13DESCRIBE `enquiry`14141
14DESCRIBE `module_types`661
15DESCRIBE `dms_companies`26261
16DESCRIBE `dms_releases`10101
17DESCRIBE `dms_categories`441
18DESCRIBE `dms_clinical_areas`441
19DESCRIBE `dms_categories_dms_releases`221
20DESCRIBE `dms_clinical_areas_dms_releases`221
21DESCRIBE `dms_releases_sites`551
22DESCRIBE `development_statuses`551
23DESCRIBE `category`14141
24DESCRIBE `categories_sites`551
25DESCRIBE `categorisation`882
26DESCRIBE `licopps_sites`331
27DESCRIBE `service`15151
28DESCRIBE `press_release`13131
29DESCRIBE `press_releases_sites`551
30DESCRIBE `story`12121
31DESCRIBE `sites_stories`551
32DESCRIBE `story_assoc`441
33DESCRIBE `companies_sites`331
34DESCRIBE `categories_users`221
35DESCRIBE `authority`331
36DESCRIBE `sites_users`551
37DESCRIBE `sites`552
38SELECT `Site`.`id`, `Site`.`name`, `Site`.`email_domain`, `Site`.`short_name`, `Site`.`brand` FROM `sites` AS `Site` WHERE `Site`.`id` = 1 LIMIT 1111
39SELECT `Category`.`uid`, `Category`.`name` FROM `category` AS `Category` LEFT JOIN `category` AS `Parent` ON (`Category`.`parent` = `Parent`.`uid`) LEFT JOIN `categories_sites` AS `CategorySite` ON (`CategorySite`.`category_id` = `Category`.`uid`) WHERE `CategorySite`.`site_id` = 1 AND `Category`.`parent` = 297 AND `Category`.`restricted` IS NULL ORDER BY `Category`.`name` ASC 881
40SELECT `Child`.`uid`, `Child`.`name`, `Child`.`parent`, `Child`.`has_children`, `Child`.`show_children`, `Child`.`show_grandchildren`, `Child`.`members`, `Child`.`num_children`, `Child`.`root`, `Child`.`restricted`, `Child`.`clan`, `Child`.`lft`, `Child`.`rgt`, `Child`.`level` FROM `category` AS `Child` WHERE `Child`.`parent` IN (505, 303, 432, 319, 798, 453, 298, 805) ORDER BY `name` ASC 67670
41SELECT `Category`.`uid`, `Category`.`name` FROM `category` AS `Category` LEFT JOIN `category` AS `Parent` ON (`Category`.`parent` = `Parent`.`uid`) LEFT JOIN `categories_sites` AS `CategorySite` ON (`CategorySite`.`category_id` = `Category`.`uid`) WHERE `CategorySite`.`site_id` = 1 AND `Category`.`parent` = 651 AND `Category`.`restricted` IS NULL ORDER BY `Category`.`name` ASC 25259
42SELECT `Child`.`uid`, `Child`.`name`, `Child`.`parent`, `Child`.`has_children`, `Child`.`show_children`, `Child`.`show_grandchildren`, `Child`.`members`, `Child`.`num_children`, `Child`.`root`, `Child`.`restricted`, `Child`.`clan`, `Child`.`lft`, `Child`.`rgt`, `Child`.`level` FROM `category` AS `Child` WHERE `Child`.`parent` IN (2049, 1623, 1624, 1625, 2131, 1626, 2132, 1627, 1628, 1629, 1630, 2134, 652, 653, 1631, 2130, 2133, 1633, 1638, 1634, 1635, 1636, 1637, 1639, 1640) ORDER BY `name` ASC 000
43SELECT `DevelopmentStatus`.`id`, `DevelopmentStatus`.`name` FROM `development_statuses` AS `DevelopmentStatus` WHERE 1 = 1 GROUP BY `DevelopmentStatus`.`id`, `DevelopmentStatus`.`name` ORDER BY `DevelopmentStatus`.`display_order` ASC 991
44SELECT c.lft, c.rgt FROM category c WHERE c.uid = 651111
45SELECT c.uid, c.name, c.level FROM category c WHERE c.lft <= "3505" AND c.rgt >= "3556" AND c.level > 1 ORDER BY c.level 111
46SELECT `TherapeuticTarget`.`lft`, `TherapeuticTarget`.`rgt`, `TherapeuticTarget`.`uid` FROM `category` AS `TherapeuticTarget` LEFT JOIN `category` AS `Parent` ON (`TherapeuticTarget`.`parent` = `Parent`.`uid`) LEFT JOIN `categories_sites` AS `CategorySite` ON (`CategorySite`.`category_id` = `TherapeuticTarget`.`uid`) WHERE `CategorySite`.`site_id` = 1 AND `TherapeuticTarget`.`uid` = 651 LIMIT 1111
47SELECT `Category`.`uid`, `Category`.`name`, `Category`.`parent`, `Category`.`has_children`, `Category`.`show_children`, `Category`.`show_grandchildren`, `Category`.`members`, `Category`.`num_children`, `Category`.`root`, `Category`.`restricted`, `Category`.`clan`, `Category`.`lft`, `Category`.`rgt`, `Category`.`level`, `Categorisation`.`id`, `Categorisation`.`company_id`, `Categorisation`.`buysell`, `Categorisation`.`category_id`, `Categorisation`.`browse_category_id`, `Categorisation`.`cat_type`, `Categorisation`.`story_id`, `Categorisation`.`network_id` FROM `category` AS `Category` JOIN `categorisation` AS `Categorisation` ON (`Categorisation`.`company_id` IN (5660, 4649, 4634, 4849, 2711, 18790, 4895, 4894, 4532, 4259) AND `Categorisation`.`category_id` = `Category`.`uid`) WHERE cat_type="L" ORDER BY `Category`.`root` ASC, `Category`.`clan` ASC, `Category`.`parent` ASC, `Category`.`name` ASC 85851
48SELECT `TherapeuticTarget`.`uid`, `TherapeuticTarget`.`name`, `TherapeuticTarget`.`parent`, `TherapeuticTarget`.`has_children`, `TherapeuticTarget`.`show_children`, `TherapeuticTarget`.`show_grandchildren`, `TherapeuticTarget`.`members`, `TherapeuticTarget`.`num_children`, `TherapeuticTarget`.`root`, `TherapeuticTarget`.`restricted`, `TherapeuticTarget`.`clan`, `TherapeuticTarget`.`lft`, `TherapeuticTarget`.`rgt`, `TherapeuticTarget`.`level`, `Categorisation`.`id`, `Categorisation`.`company_id`, `Categorisation`.`buysell`, `Categorisation`.`category_id`, `Categorisation`.`browse_category_id`, `Categorisation`.`cat_type`, `Categorisation`.`story_id`, `Categorisation`.`network_id` FROM `category` AS `TherapeuticTarget` JOIN `categorisation` AS `Categorisation` ON (`Categorisation`.`company_id` IN (5660, 4649, 4634, 4849, 2711, 18790, 4895, 4894, 4532, 4259) AND `Categorisation`.`category_id` = `TherapeuticTarget`.`uid`) WHERE `cat_type` = 'L' ORDER BY `TherapeuticTarget`.`root` ASC, `TherapeuticTarget`.`clan` ASC, `TherapeuticTarget`.`parent` ASC, `TherapeuticTarget`.`name` ASC 85853
(website_slave) 2 queries took 838 ms
NrQueryErrorAffectedNum. rowsTook (ms)
1SELECT `Outlicensing`.`uid`, `Outlicensing`.`slug`, `Outlicensing`.`title`, `Outlicensing`.`shortdesc` FROM `licopp` AS `Outlicensing` INNER JOIN company AS `ParentCompany` ON (`ParentCompany`.`uid`=`Outlicensing`.`company_id` AND `ParentCompany`.`is_live`="Y") INNER JOIN categorisation AS `CategorisationTherapeuticTarget` ON (`CategorisationTherapeuticTarget`.`company_id` = `Outlicensing`.`uid` AND `CategorisationTherapeuticTarget`.`cat_type` = 'L') INNER JOIN category AS `TherapeuticTarget` ON (`TherapeuticTarget`.`uid` = `CategorisationTherapeuticTarget`.`category_id` AND `TherapeuticTarget`.`lft` >= '3505' AND `TherapeuticTarget`.`rgt` <= '3556') LEFT JOIN `development_statuses` AS `DevelopmentStatus` ON (`Outlicensing`.`devstatus` = `DevelopmentStatus`.`id`) LEFT JOIN `licopps_sites` AS `OutlicensingSite` ON (`OutlicensingSite`.`licopp_id` = `Outlicensing`.`uid`) WHERE `OutlicensingSite`.`site_id` = 1 AND `Outlicensing`.`is_out` = 'Y' AND ((`TherapeuticTarget`.`lft` >= 3505) AND (`TherapeuticTarget`.`rgt` <= 3556)) GROUP BY `Outlicensing`.`uid` ORDER BY `Outlicensing`.`viewed_counter` DESC, `Outlicensing`.`title` ASC LIMIT 101010546
2SELECT COUNT(DISTINCT Outlicensing.uid) AS `count` FROM `licopp` AS `Outlicensing` INNER JOIN company AS `ParentCompany` ON (`ParentCompany`.`uid`=`Outlicensing`.`company_id` AND `ParentCompany`.`is_live`="Y") INNER JOIN categorisation AS `CategorisationTherapeuticTarget` ON (`CategorisationTherapeuticTarget`.`company_id` = `Outlicensing`.`uid` AND `CategorisationTherapeuticTarget`.`cat_type` = 'L') INNER JOIN category AS `TherapeuticTarget` ON (`TherapeuticTarget`.`uid` = `CategorisationTherapeuticTarget`.`category_id` AND `TherapeuticTarget`.`lft` >= '3505' AND `TherapeuticTarget`.`rgt` <= '3556') LEFT JOIN `development_statuses` AS `DevelopmentStatus` ON (`Outlicensing`.`devstatus` = `DevelopmentStatus`.`id`) LEFT JOIN `licopps_sites` AS `OutlicensingSite` ON (`OutlicensingSite`.`licopp_id` = `Outlicensing`.`uid`) WHERE `OutlicensingSite`.`site_id` = 1 AND `Outlicensing`.`is_out` = 'Y' AND ((`TherapeuticTarget`.`lft` >= 3505) AND (`TherapeuticTarget`.`rgt` <= 3556)) 11292
(default) 0 query took ms
NrQueryErrorAffectedNum. rowsTook (ms)
(report) 1 query took 1 ms
NrQueryErrorAffectedNum. rowsTook (ms)
1DESCRIBE `reports`17171
(report_slave) 1 query took 1 ms
NrQueryErrorAffectedNum. rowsTook (ms)
1SELECT `MarketResearchReport`.`id`, `MarketResearchReport`.`slug`, `MarketResearchReport`.`name`, `MarketResearchReport`.`description`, `MarketResearchReport`.`summary`, `MarketResearchReport`.`content`, `MarketResearchReport`.`isbn`, `MarketResearchReport`.`code`, `MarketResearchReport`.`pages`, `MarketResearchReport`.`published`, `MarketResearchReport`.`net_price_usd`, `MarketResearchReport`.`active`, `MarketResearchReport`.`publisher_id`, `MarketResearchReport`.`views`, `MarketResearchReport`.`tags`, `MarketResearchReport`.`created`, `MarketResearchReport`.`modified` FROM `reports` AS `MarketResearchReport` WHERE `MarketResearchReport`.`active` = 1 AND MATCH (`MarketResearchReport`.`name`, `MarketResearchReport`.`description`, `MarketResearchReport`.`summary`, `MarketResearchReport`.`content`, `MarketResearchReport`.`isbn`, `MarketResearchReport`.`code`) AGAINST ("Immune related disorders") ORDER BY MATCH (`MarketResearchReport`.`name`, `MarketResearchReport`.`description`, `MarketResearchReport`.`summary`, `MarketResearchReport`.`content`, `MarketResearchReport`.`isbn`, `MarketResearchReport`.`code`) AGAINST ("Immune related disorders") DESC , MarketResearchReport.published DESC LIMIT 1010101