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Articles

Innovaro Pharmalicensing brings you advice, commentary and analysis from industry experts.

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Harvard oncomouse - the EPO's latest word

The 'Harvard Oncomouse' patent claimed a method for producing transgenic non-human mammals with a predisposition to developing cancer. The prospect of the commercialisation of animals fated to develop cancer was the cause of significant protest. More

Armed antibodies

The discovery by Kohler and Milstein in 1975 that it was possible to generate monoclonal antibodies via hybridoma technology sparked a scientific revolution - and the consequences have been awesome More

ESBATech: Therapeutic antibody fragments for local applications

ESBATech is drug discovery company, exploiting its expertise in yeast technology for the development of therapeutic antibody fragments and the development of functional assays for small molecule screenings More

Interview with Cambridge Antibody Technology Medical Director David Glover

This interview charts the progress of CAT from its formation in 1990 to the present day. More

Emerging therapeutic targets in asthma and allergy: modulation of IgE

In the past thirty years the prevalence of allergicdisorders, especially asthma, has risen steadily in the world. This paper covers new immunotherapy approaches using immunoglobin as the target. More

Accelerating R&D Productivity

The potential of the post genomic era has not yet translated into new levels of drug discovery. This talk will explore various hypotheses to explain the conundrum. More

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(website) 47 queries took 768 ms
Nr	Query	Affected	Num. rows	Took (ms)
1	DESCRIBE `feature_article`	13	13	5
2	DESCRIBE `feature_author`	13	13	18
3	DESCRIBE `user`	24	24	18
4	DESCRIBE `condet`	17	17	8
5	DESCRIBE `countrycode`	4	4	27
6	DESCRIBE `company`	27	27	8
7	DESCRIBE `person`	15	15	17
8	DESCRIBE `account`	29	29	18
9	DESCRIBE `product_legacy`	6	6	25
10	DESCRIBE `sales_people`	6	6	19
11	DESCRIBE `profile`	14	14	11
12	DESCRIBE `currencies`	7	7	10
13	DESCRIBE `update_rec`	7	7	8
14	DESCRIBE `dms_companies`	26	26	21
15	DESCRIBE `dms_releases`	10	10	24
16	DESCRIBE `dms_categories`	4	4	9
17	DESCRIBE `dms_clinical_areas`	4	4	6
18	DESCRIBE `dms_categories_dms_releases`	2	2	5
19	DESCRIBE `dms_clinical_areas_dms_releases`	2	2	13
20	DESCRIBE `dms_releases_sites`	5	5	6
21	DESCRIBE `licopp`	23	23	22
22	DESCRIBE `development_statuses`	5	5	22
23	DESCRIBE `category`	14	14	9
24	DESCRIBE `categories_sites`	5	5	9
25	DESCRIBE `categorisation`	8	8	18
26	DESCRIBE `licopps_sites`	3	3	3
27	DESCRIBE `service`	15	15	17
28	DESCRIBE `enquiry`	14	14	27
29	DESCRIBE `module_types`	6	6	11
30	DESCRIBE `press_release`	13	13	18
31	DESCRIBE `press_releases_sites`	5	5	32
32	DESCRIBE `story`	12	12	4
33	DESCRIBE `sites_stories`	5	5	32
34	DESCRIBE `story_assoc`	4	4	4
35	DESCRIBE `companies_sites`	3	3	10
36	DESCRIBE `categories_users`	2	2	16
37	DESCRIBE `authority`	3	3	9
38	DESCRIBE `sites_users`	5	5	18
39	DESCRIBE `sites`	5	5	15
40	SELECT `Site`.`id`, `Site`.`name`, `Site`.`email_domain`, `Site`.`short_name`, `Site`.`brand` FROM `sites` AS `Site` WHERE `Site`.`id` = 1 LIMIT 1	1	1	12
41	SELECT c.uid, c.name FROM category c WHERE c.parent = 805 ORDER BY c.name	7	7	8
42	SELECT c.uid, c.name FROM category c WHERE c.parent = 560 ORDER BY c.name	20	20	20
43	SELECT DISTINCT SUBSTRING(issued, 1, 4) AS publication_year FROM feature_article AS Article WHERE is_live = 1 AND issued IS NOT NULL ORDER BY publication_year DESC	13	13	2
44	SELECT c.lft, c.rgt FROM category c WHERE c.uid = 805	1	1	1
45	SELECT c.uid, c.name, c.level FROM category c WHERE c.lft <= "1915" AND c.rgt >= "1930" AND c.level > 1 ORDER BY c.level	1	1	0
46	SELECT feature_article.uid, feature_article.headline, feature_article.summary, feature_article.slug FROM feature_article INNER JOIN categorisation is_ctg ON is_ctg.story_id = feature_article.uid AND is_ctg.cat_type = "F" AND is_ctg.category_id IN (SELECT uid FROM category WHERE (lft >= 1915 AND rgt <= 1930) ) WHERE feature_article.is_live > 0 GROUP BY feature_article.uid ORDER BY feature_article.viewed_counter DESC, feature_article.headline LIMIT 0, 10	6	6	106
47	SELECT count(DISTINCT feature_article.uid) AS total FROM feature_article INNER JOIN categorisation is_ctg ON is_ctg.story_id = feature_article.uid AND is_ctg.cat_type = "F" AND is_ctg.category_id IN (SELECT uid FROM category WHERE (lft >= 1915 AND rgt <= 1930) ) WHERE feature_article.is_live > 0	1	1	47

(website) 47 queries took 768 ms

Query

Error

Affected

Num. rows

Took (ms)

DESCRIBE `feature_article`

DESCRIBE `feature_author`

DESCRIBE `user`

DESCRIBE `condet`

DESCRIBE `countrycode`

DESCRIBE `company`

DESCRIBE `person`

DESCRIBE `account`

DESCRIBE `product_legacy`

DESCRIBE `sales_people`

DESCRIBE `profile`

DESCRIBE `currencies`

DESCRIBE `update_rec`

DESCRIBE `dms_companies`

DESCRIBE `dms_releases`

DESCRIBE `dms_categories`

DESCRIBE `dms_clinical_areas`

DESCRIBE `dms_categories_dms_releases`

DESCRIBE `dms_clinical_areas_dms_releases`

DESCRIBE `dms_releases_sites`

DESCRIBE `licopp`

DESCRIBE `development_statuses`

DESCRIBE `category`

DESCRIBE `categories_sites`

DESCRIBE `categorisation`

DESCRIBE `licopps_sites`

DESCRIBE `service`

DESCRIBE `enquiry`

DESCRIBE `module_types`

DESCRIBE `press_release`

DESCRIBE `press_releases_sites`

DESCRIBE `story`

DESCRIBE `sites_stories`

DESCRIBE `story_assoc`

DESCRIBE `companies_sites`

DESCRIBE `categories_users`

DESCRIBE `authority`

DESCRIBE `sites_users`

DESCRIBE `sites`

SELECT `Site`.`id`, `Site`.`name`, `Site`.`email_domain`, `Site`.`short_name`, `Site`.`brand` FROM `sites` AS `Site` WHERE `Site`.`id` = 1 LIMIT 1

SELECT c.uid, c.name FROM category c WHERE c.parent = 805 ORDER BY c.name

SELECT c.uid, c.name FROM category c WHERE c.parent = 560 ORDER BY c.name

SELECT DISTINCT SUBSTRING(issued, 1, 4) AS publication_year FROM feature_article AS Article WHERE is_live = 1 AND issued IS NOT NULL ORDER BY publication_year DESC

SELECT c.lft, c.rgt FROM category c WHERE c.uid = 805

SELECT c.uid, c.name, c.level FROM category c WHERE c.lft <= "1915" AND c.rgt >= "1930" AND c.level > 1 ORDER BY c.level

SELECT feature_article.uid, feature_article.headline, feature_article.summary, feature_article.slug FROM feature_article INNER JOIN categorisation is_ctg ON is_ctg.story_id = feature_article.uid AND is_ctg.cat_type = "F" AND is_ctg.category_id IN (SELECT uid FROM category WHERE (lft >= 1915 AND rgt <= 1930) ) WHERE feature_article.is_live > 0 GROUP BY feature_article.uid ORDER BY feature_article.viewed_counter DESC, feature_article.headline LIMIT 0, 10

106

SELECT count(DISTINCT feature_article.uid) AS total FROM feature_article INNER JOIN categorisation is_ctg ON is_ctg.story_id = feature_article.uid AND is_ctg.cat_type = "F" AND is_ctg.category_id IN (SELECT uid FROM category WHERE (lft >= 1915 AND rgt <= 1930) ) WHERE feature_article.is_live > 0

(report) 1 query took 1 ms
Nr	Query	Error	Affected	Num. rows	Took (ms)
1	DESCRIBE `reports`		17	17	1

(report) 1 query took 1 ms

Query

Error

Affected

Num. rows

Took (ms)

DESCRIBE `reports`

(report_slave) 1 query took 34 ms
Nr	Query	Error	Affected	Num. rows	Took (ms)
1	SELECT `MarketResearchReport`.`id`, `MarketResearchReport`.`slug`, `MarketResearchReport`.`name`, `MarketResearchReport`.`description`, `MarketResearchReport`.`summary`, `MarketResearchReport`.`content`, `MarketResearchReport`.`isbn`, `MarketResearchReport`.`code`, `MarketResearchReport`.`pages`, `MarketResearchReport`.`published`, `MarketResearchReport`.`net_price_usd`, `MarketResearchReport`.`active`, `MarketResearchReport`.`publisher_id`, `MarketResearchReport`.`views`, `MarketResearchReport`.`tags`, `MarketResearchReport`.`created`, `MarketResearchReport`.`modified` FROM `reports` AS `MarketResearchReport` WHERE `MarketResearchReport`.`active` = 1 AND MATCH (`MarketResearchReport`.`name`, `MarketResearchReport`.`description`, `MarketResearchReport`.`summary`, `MarketResearchReport`.`content`, `MarketResearchReport`.`isbn`, `MarketResearchReport`.`code`) AGAINST ("Research tools") ORDER BY MATCH (`MarketResearchReport`.`name`, `MarketResearchReport`.`description`, `MarketResearchReport`.`summary`, `MarketResearchReport`.`content`, `MarketResearchReport`.`isbn`, `MarketResearchReport`.`code`) AGAINST ("Research tools") DESC , MarketResearchReport.published DESC LIMIT 10		10	10	34

(report_slave) 1 query took 34 ms

Query

Error

Affected

Num. rows

Took (ms)

SELECT `MarketResearchReport`.`id`, `MarketResearchReport`.`slug`, `MarketResearchReport`.`name`, `MarketResearchReport`.`description`, `MarketResearchReport`.`summary`, `MarketResearchReport`.`content`, `MarketResearchReport`.`isbn`, `MarketResearchReport`.`code`, `MarketResearchReport`.`pages`, `MarketResearchReport`.`published`, `MarketResearchReport`.`net_price_usd`, `MarketResearchReport`.`active`, `MarketResearchReport`.`publisher_id`, `MarketResearchReport`.`views`, `MarketResearchReport`.`tags`, `MarketResearchReport`.`created`, `MarketResearchReport`.`modified` FROM `reports` AS `MarketResearchReport` WHERE `MarketResearchReport`.`active` = 1 AND MATCH (`MarketResearchReport`.`name`, `MarketResearchReport`.`description`, `MarketResearchReport`.`summary`, `MarketResearchReport`.`content`, `MarketResearchReport`.`isbn`, `MarketResearchReport`.`code`) AGAINST ("Research tools") ORDER BY MATCH (`MarketResearchReport`.`name`, `MarketResearchReport`.`description`, `MarketResearchReport`.`summary`, `MarketResearchReport`.`content`, `MarketResearchReport`.`isbn`, `MarketResearchReport`.`code`) AGAINST ("Research tools") DESC , MarketResearchReport.published DESC LIMIT 10